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MAbs Turn 30
Is one of modern biology's most sophisticated tools ready for an update?
Email: Mark Greener - mgreener@the-scientist.com The Scientist 2005, 19(3):14
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Thirty years ago, César Milstein and Georges Köhler, two researchers at the Medical Research Council's (MRC) Laboratory of Molecular Biology in Cambridge, were investigating the mechanisms underlying the remarkable diversity of antibodies. As part of their research they constructed a continuously growing cell line expressing a specific, predefined antibody.[1]
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