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RNA pol does double duty
The Scientist 2005, 19(4):24
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The paradoxical involvement of RNA-mediated gene silencing in the maintenance of some DNA silencing is bridged in Arabidopsis by an RNA polymerase that acts as a liaison between both pathways, according to UK researchers. Alan Herr, from the John Innes Centre, Norwich, and colleagues found that mutants for RNA polymerase IV (Pol IV, also called RPD1), part of a new clade of polymerases in plants, were defective in both RNA and DNA silencing.[1]
"The finding of a new silencing-specific RNA polymerase is a surprising twist in the evolution of RNA polymerases," Herr writes in an E-mail.
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