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Protein PCR with Chimeric "Tadpoles"
DNA-protein hybrid molecules offer high-sensitivity detection of non-DNA targets
The Scientist 2005, 19(4):36
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DNA has its PCR, but no comparable method exists for high-sensitivity detection of proteins. Now, a new class of protein-DNA chimeras, dubbed "tadpoles," could fill that void.[1]
"Call this PCR for proteins and other molecules," says coauthor Roger Brent of the Molecular Sciences Institute in Berkeley, Calif.
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