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The Scientist 2005, 19(7):12
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In the fall of 2003, researchers at the Dana-Farber Cancer Institute and Brigham and Women's Hospital in Boston were facing a problem. They were trying to study the genetic underpinnings of three myeloproliferative disorders (MPDs), and they needed blood samples and cheek swabs from hundreds of patients. However, as the diseases are relatively rare, affecting fewer than 100,000 people in the United States, they had gathered only a handful of samples from patients visiting their institutions over a period of six months. At that rate, the researchers feared they would never finish.
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