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Survival's Signature
Gene-expression profiling of adenocarcinomas reveals prognostic indicators and hallmarks of metastasis
Email: Nicole Johnston - njohnston@the-scientist.com The Scientist 2005, 19(7):20
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Metastasis, the leading cause of cancer deaths, remains a poorly understood phenomenon. In early-stage lung cancer, for example, 25% to 30% of patients will succumb to the disease even though the tumors are small and detected early. The use of gene-expression analyses has allowed the opportunity to ask whether these high-risk stage I lung cancers can be distinguished from benign tumors so that these patients might receive more aggressive therapy.
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