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Tissue Microarrays Go Mainstream
This former "next big thing" is now a standard molecular profiling tool
Email: Anne Harding - aharding@the-scientist.com The Scientist 2005, 19(7):26
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The biggest news these days in tissue microarrays (TMAs) may be that this former "next big thing" has become a standard tool for molecular profiling of disease. Some 682 papers have been published on TMAs, according to the ISI Web of Science, two-thirds of them on cancer. The technology has helped move at least one biomarker – racemase, for prostate cancer – into the clinic. Their usefulness for gene marker validation is broadly accepted, and some in the field see TMAs as platforms for multimarker discovery in their own right.
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