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A Peek at the Pore
Scientists begin to fill in the blanks for the nuclear pore complex
Email: Bennett Daviss - bdaviss@the-scientist.com The Scientist 2005, 19(8):18
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As the gateway to the nucleus, the nuclear pore complex manages hundreds of intricate cargo-handling operations every second. It decides which molecules enter the 120-nm long channel leading to the nucleus. The NPC ferries pairs of proteins as small as 50,000 daltons from cytoplasm to nucleus and shuttles ribosomal subunits as massive as 2 megadaltons going the opposite way.
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