Three decades and 6,000 papers since the term was first coined, scientists are still debating the mechanisms of long-term potentiation (LTP).[1] Defined in 1973 as an increase in synaptic strength following experimentally induced high-frequency stimulation,[2] LTP has been consistently controversial. Now at last, "There is a consensus beginning to emerge," says Columbia University Nobel laureate, Eric Kandel, as years of research have begun to make sense of what once seemed irreconcilable contradictions. An almost decade-long argument over whether LTP should be considered presynaptic or postsynaptic now appears settled, allowing researchers to pursue finer details.