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Signs of selection in genes
The Scientist 2005, 19(10):26
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In the estimated 5 million years since humans and chimpanzees began diverging, they've acquired major anatomical and cognitive differences. Nevertheless, some of the strongest evidence for positive selection since divergence appears to be for genes related to immunological defense and apoptosis. Building on an earlier study, Cornell University's Rasmus Nielsen and colleagues compared over 13,000 annotated human genes and their chimp equivalents, looking to the ratio of synonymous to nonsynonymous mutations as evidence of positive selection.[1]
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