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Catalase extends mouse lifespan
The Scientist 2005, 19(11):28
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Mice engineered to produce high levels of the antioxidant catalase live longer than their wild-type counterparts. Researchers observed the largest lifespan extension when they targeted the enzyme to mitochondria. The results lend support to the free-radical theory of aging, which attributes many of the infirmities of old age to accumulated cellular damage caused by reactive oxygen species and the free radicals they generate.
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