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Genes jumping in the brain
The Scientist 2005, 19(13):27
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Genetic elements that jump around the genome can influence brain circuitry, according to US researchers. In a study of adult rat hippocampal neural stem cells, Fred Gage and colleagues at the Salk Institute for Biological Studies in La Jolla, Calif., discovered an up to twofold enrichment of the transcripts of retrotransposons known as L1 elements.[1]
"This is the first evidence [that retrotransposition] events might be occurring in developing neurons seen in the adult brain," says Haig Kazazian at the University of Pennsylvania.
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