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Another Kind of Antigen
Lipid antigens blur the roles of acquired immunity
Email: Jill U Adams - juadams@the-scientist.com The Scientist 2005, 19(14):15
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The discovery that lipids can serve as antigens first stunned the immunological community a decade ago. But following the initial shock that floppy, hydrophobic hydrocarbon chains could stir a T-lymphocyte reaction with the same specificity as the peptides presented by conventional major histocompatibility complex (MHC) molecules, researchers hunkered down to determine the new mechanisms.
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