Advertisement
Survey Series
Institutions
For Advertisers
|
|
||||
|
Non-stimulatory stimulation
The Scientist 2005, 19(14):26
|
||||
|
|
||||
|
Healthy immune systems are supposed to ignore self-molecules when looking for foreign invaders. But researchers at the Scripps Institute in, La Jolla, Calif., have shown that non-stimulatory peptides, including self-peptides, interact with the CD8 coreceptor to help the T-cell receptor (TCR) find its target antigen[1]
. David Kranz of the University of Illinois, Urbana-Champaign says, "It's been kind of a puzzle: How can only a few [antigenic] peptide MHCs stimulate a T cell?"
|
|
|||||||||
|
|||||||||
|
