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The Delicate Toxicity Balance in Drug Discovery
Can pricey late-stage failures – or dangerous drugs – be prevented with better products for predicting drug toxicity?
Email: Usha Sankar - usankar@the-scientist.com The Scientist 2005, 19(15):32
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In 2000, the type 2 diabetes drug Rezulin was withdrawn from the market after several dozen patients required a liver transplant or died due to liver failure. While the vast majority of drugs that make it to market are safe, such high-profile failures show that the drug development process is far from flawless.
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