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The Business of Building Leaders
Rational design is better than random screening when it comes to selecting scientific leaders
Email: Benjamin Doranz - bdoranz@integralmolecular.com The Scientist 2005, 19(15):40
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Cultivating scientific leaders is a bit like drug discovery. To produce a drug, two different, but complementary, strategies are employed: random screening, to isolate the one-out-of-a-millioncompounds with the best traits; and rational design, to further improve those traits inherent to the initial structure. These synergistic approaches are the cornerstones of modern drug discovery, but reliance on either one alone rarely yields the final desired result.
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