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Institutions
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Polarity Pathways Make a Connection
Studies piece together conserved signals for orientation and migration
Email: Ishani Ganguli - iganguli@the-scientist.com The Scientist 2005, 19(17):22
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Before a cell can do its job, it needs to get oriented. Cells must determine their purpose in life, tell their tops from their bottoms, and quite literally find their place amidst a confusing array of physical and chemical signals. Cell polarization meets these challenges. Spatial segregation assumes different roles in embryonic cells, epithelial cells, and neural precursors. And each cell type relies on a complex web of signal-transduction events to establish asymmetry.
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