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Models for HCV
The Scientist 2005, 19(17):24
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Without a sufficient cell culture system, researchers have had little success designing and testing drugs for the treatment of the hepatitis C virus (HCV). Now, a recent paper describes an HCV genome that was isolated from a patient with fulminant hepatitis and supports both RNA replication and secretion of viral particles upon transfection in a human liver cell line (Huh7).
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