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New Arrays Open 'Junk DNA' to Exploration
Affymetrix and NimbleGen begin commercialization of whole-genome tiling arrays
Email: Lissa Harris - lharris@the-scientist.com The Scientist 2005, 19(19):36
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Microarrays present researchers with something of a catch-22: In order to find something, you have to know what you're looking for. If you're looking for new functional elements, your microarray needs to contain probes designed to target them. With many transcribed regions, protein-binding sites, and even genes still missing from genome annotations, however, even so-called "whole-genome" arrays with millions of features are likely to miss critical sequences.
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