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Tissue Microarrays Go Coreless
New technique increases feature density, decreases variability
The Scientist 2005, 19(19):38
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To study tissue samples from multiple patients, researchers use tissue microarrays (TMAs), a technology in which hundreds of tissue cores are arranged on a single glass slide for analysis by immunostaining or in situ hybridization. TMAs typically are prepared by punching cores out of paraffin-embedded tissue blocks and relocating them in specific positions in a new block, which is then sliced to produce dozens of slides.
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