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Genes Get a PiggyBac Ride
Newly identified transposon can knock out mammalian genes
The Scientist 2005, 19(21):32
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Transposons are often likened to genetic parasites – rarely benefit the organisms in whose genomes they appear – they have been a boon to scientists. Geneticists have been using these "jumping genes" to knock out (and smuggle in) sequences in such model organisms as Drosophila and Arabidopsis for decades. Transposons that function in mammals have proved far more elusive, however.
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