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Hormonal sibling rivalry
The Scientist 2005, 19(23):28
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Proteins that stimulate and repress appetite appear to be cut from the same cloth. Stanford University biologists report that a newly discovered appetite suppressing hormone, called obestatin, is produced by posttranslational modification of a protein precursor that also gives rise to ghrelin, an appetite stimulator.[1]
The authors suggest this work may provide new targets for controlling obesity, as well as resolve an outstanding mystery surrounding ghrelin knockout mice.
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