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Reconstructing Mammalian Cell Lineages
Computational technique tracks cell fate in mice and men
The Scientist 2005, 19(23):38
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Adult nematode worms contain 959 somatic cells, and thanks to Nobel laureate John Sulston and colleagues, scientists know the lineage of every one of them. Cell fate maps have never been built for higher metazoans, however. "People thought it would be too unwieldy and useless to try," says Ricardo Azevedo, a developmental biologist at the University of Houston.
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