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The autism gene problem
Virginia Tech, Blacksburg, VA.Email: Thomas P Caruso - tcaruso@vt.edu The Scientist 2005, 19(23):8
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I wonder why we are still asking questions like "How do you find genes for a disorder that eludes definition?"[1]
You even suggest the solution when you quote Steve Scherer saying that "while...neurolignin could be a candidate in some rare cases, other researchers have countered that the family where the gene was found may have mental retardation rather than autism." The answer is to look at candidate genes and find out what symptoms are phenotypically unique to people who have a particular variant of the gene compared with people who don't have that variant.
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