Making Do with the Bare Minimum

Interrogating bacteria for their essential gene sets

All the information needed to make a cell is in a handful of genes for protein synthesis, some for DNA and RNA metabolism, a few for making the envelope, and a smattering of others. Estimates of the total number of so-called essential genes vary greatly by organism and the screen used to make the determination, and even the definition of essential genes may be variable. Yet the potential in tracking down these bits of code is undeniable.

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