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by Praxis Press

RESEARCH ROUND-UP

Sickle-cell anemia treatment

Sodium cromoglicate is a treatment option for sickle-cell anemia.

News from The Scientist 2000, 1(1):20000725-02

NEW YORK, July 24 (Praxis Press) Previous reports have documented that sodium cromoglicate has antisickling activity in vitro. Toppet and colleagues studied this antisickling activity in sickle-cell patients given sodium cromoglicate by inhalation or nasal route. Both treatments significantly decreased the percentage of sickle cells in venous blood; this effect was largely retained when the blood was deoxygenated. Sodium cromoglicate may be a clinically useful antisickling drug that has the added benefits of low toxicity and low cost.


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