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The sticking place
A long-sought receptor on platelets, that binds ADP and is targeted by antithrombotic drugs, has been identified and cloned.
Email: Tudor Toma - ttoma@mail.dntis.ro News from The Scientist 2001, 2(1):20010111-02
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Platelets are central to the process of wound healing. But overly responsive platelets could block normal blood flow, particularly where atherosclerosis exists, resulting in stroke, myocardial infarction and unstable angina. Hence the interest in studying the receptors for platelet-activating substances released from damaged vessels, like ADP.
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