The Scientist : more than just a problem with chloride ions [1/3/2001]

Cystic fibrosis — more than just a problem with chloride ions

Email: Kenneth Lee - kenlee_fr@yahoo.fr
News from The Scientist 2001, 2(1):20010301-03

1 March 2001

Cystic fibrosis (CF) is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR), which forms a chloride ion (Cl^-) transport channel in epithelial cells. But the existence of some CF patients with normal Cl^- ion channel activity has puzzled researchers for some time.

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