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Making sense of antisense
A strategy combining antisense RNA and promoter interference technology allows for genome-wide screening of gene function in Candida albicans.
Email: Jonathan Weitzman - jonathanweitzman@hotmail.com News from The Scientist 2001, 2(1):20010308-01
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The yeast Candida albicans is the major pathogen causing human fungal infections. C. albicans is not amenable to functional genomic strategies used for other micro-organisms, because of mating difficulties, its diploid nature and the lack of random insertional mutagenesis methods.
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