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Postnatal steroid treatment increases neuro-developmental impairment
Steroid therapy administered to prevent or treat bronchopulmonary dysplasia is associated with an increase in cerebral palsy and neuro-developmental impairment in preterm infants.
Email: Tudor Toma - ttoma@mail.dntis.ro News from The Scientist 2001, 2(1):20010316-04
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Postnatal administration of corticosteroids for treatment and prevention of chronic lung disease such as bronchopulmonary dysplasia is a widespread practice and to date there have been no adequate analyses of long-term adverse effects. According to a meta-analysis just published in BMC Pediatrics, postnatal steroid treatment is associated with dramatic increases in neuro-developmental impairment and steroid use to prevent or treat bronchopulmonary dysplasia should be abandoned (BMC Pediatrics 2001, 1:1).
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