The Scientist : Mouse model of a human neurological disorder [2/4/2001]

Mouse model of a human neurological disorder

Mice lacking the NF1 gene product have some of the symptoms of neurofibromatosis type 1, a common neurological disorder in humans.

Email: Kenneth Lee - kenlee_fr@yahoo.fr
News from The Scientist 2001, 2(1):20010402-03

Published

2 April 2001

Neurofibromatosis type 1 (NF1) is an inherited neurological disorder that affects 1 in 3,500 people worldwide. It is caused by mutations in the NF1 gene, which encodes neurofibromin, a protein involved in the Ras signalling pathway. Patients have tumours of neural origin and many have learning difficulties.

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