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Deficient domain protein reveal pathway for cardiomyopathy
Email: Tudor Toma - ttoma@mail.dntis.ro News from The Scientist 2001, 2(1):20010501-02
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Cytoskeletal mutations have been implicated in the genetically based forms of dilated cardiomyopathy, but the mechanisms by which heart failure develops is not known. In May Nature Medicine Mohammad Pashmforoush and colleagues from the University of California at San Diego, La Jolla, California suggest a novel developmental pathway for right ventricular dilated cardiomyopathy involving α-actinin complex instability.
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