The Scientist : Rules for receptor trafficking in the brain [9/5/2001]

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RESEARCH ROUND-UP

Rules for receptor trafficking in the brain

Glutamate receptors in hippocampus employ a variety of delivery mechanisms to stabilize long-term changes in synaptic efficacy.

Email: Tudor Toma - ttoma@mail.dntis.ro
News from The Scientist 2001, 2(1):20010509-01

AMPA-type glutamate synaptic receptors (AMPA-Rs) mediate a wide variety of excitatory synaptic transmissions in the brain. The mechanism by which these receptors maintain a long-term synaptic efficacy are not fully understood. In the 4 May Cell Song-Hai Shi and colleagues at Cold Spring Harbor Laboratory, New York show that AMPA-Rs in hippocampus use a number of delivery mechanisms to stabilize long-term changes in synaptic efficacy.


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