The Scientist : Antigen-specific T cell-mediated gene therapy [4/6/2001]

Antigen-specific T cell-mediated gene therapy

Email: Tudor Toma - ttoma@mail.dntis.ro
News from The Scientist 2001, 2(1):20010604-03

4 June 2001

Autoantigen-specific T cells have tissue-specific homing properties which make them ideal vehicles for the local delivery of immunoregulatory molecules. In May 15 Journal of Clinical Investigation Atsuo Nakajima and colleagues from Stanford University show that antigen-specific T cell-mediated gene therapy can inhibit the development of collagen-induced arthritis (CIA), a murine model of rheumatoid arthritis.

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