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A new mechanism for hypertension
Email: Jason O'Neale Roach - Jason@biomedcentral.com News from The Scientist 2001, 2(1):20010810-02
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Hypertension is an important risk factor for death from stroke, heart disease, and kidney failure and affects about one-quarter of all adults word wide. In August 10 Science, Richard Lifton and colleagues at the Howard Hughes Medical Institute, Yale University School of Medicine in America, have identified two genes that cause pseudohypoaldosteronism type II (PHAII). This disorder causes hypertension via increased reabsorption of salt by the kidneys, and impaired secretion of potassium and hydrogen ions. (Science 2001, 293:1107-1112).
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