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HIV confuses specific B cell subset
Certain B cells are targeted by the human immunodeficiency virus, leading to the characteristic hypergammaglobulinemia associated with the disease.
Email: Tudor Toma - t.toma@ic.ac.uk News from The Scientist 2001, 2(1):20010817-02
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Antibody-producing B cells begin to malfunction early after infection with HIV, for reasons that are poorly understood. In August 14 on-line Proceedings of the National Academy of Sciences Susan Moir and colleagues from National Institute of Allergy and Infectious Diseases, Bethesda, US show that HIV viremia induces the appearance of a subset of B cells whose function is impaired and which may be responsible for the hypergammaglobulinemia associated with HIV disease.
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