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Making sense of antisense
Email: Jonathan Weitzman - jonathanweitzman@hotmail.com News from The Scientist 2001, 2(1):20010820-01
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The specificity of antisense approaches is much debated and has hampered their development for clinical therapeutics. In the August 14 Proceedings of the National Academy of Sciences, Yee Cho and colleagues at the National Institutes of Health, Bethesda, MD, report the use of DNA microarrays to resolve aspects of the mechanism of antisense action (Proc Natl Acad Sci USA 2001, 98:9819-9823).
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