The Scientist : Career counselling for embryonic cells [4/9/2001]

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by Tudor Toma

RESEARCH ROUND-UP

Career counselling for embryonic cells

The extracellular sulfatase QSulf1, responds to Sonic hedgehog signaling, and is involved in embryonic cell fate determination.

Email: Tudor Toma - t.toma@ic.ac.uk
News from The Scientist 2001, 2(1):20010904-02

Published

4 September 2001

In an embryo, the stem cells develop into specific organs under the influence of complex extracellular signals. Sonic hedgehog (Shh) plays an important role in this process but its signalling pathway is not entirely understood. In August 31 Science Gurtej Dhoot and colleagues from the University of Pennsylvania Medical Center identify a member of a family of conserved sulfatases, QSulf1, which is responsive to Shh signaling and has role in embryonic cell fate determination.

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