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An innovative approach to vaccination against tumors
Fusion of chaperone protein calreticulin to HPV-16 E7 gene can generate an impressive antitumor effect.
Email: Tudor Toma - t.toma@ic.ac.uk News from The Scientist 2001, 2(1):20010907-02
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Antigen-specific cancer immunotherapy and anti-angiogenesis represent two attractive mechanisms that could be of use in the treatment of cancer. In September 1 Journal of Clinical Investigation, Wen-Fang Cheng and colleagues from Johns Hopkins University School of Medicine show an innovative vaccination approach that combines both mechanisms and suggest this is likely generate a potent antitumor effect.
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