|
|
||||
|
An antibody that blows up platelets
Email: Tudor Toma - t.toma@ic.ac.uk News from The Scientist 2001, 2(1):20010912-02
|
||||
|
|
||||
|
Immunologic thrombocytopenia, a frequent complication of HIV-1 infection, is associated with circulating immune complexes that contain platelet membrane components and anti-platelet membrane GPIIIa49-66 IgG antibodies. In September 7 Cell, Michael Nardi and colleagues from New York University School of Medicine show that anti-platelet GPIIIa49-66 IgG alone can causes platelet fragmentation independent of complement, via the induction of reactive oxygen species.
|
|
|||||||||
|
|||||||||
|