The Scientist : S-nitrosothiols control breathing [13/9/2001]

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by Tudor Toma

RESEARCH ROUND-UP

S-nitrosothiols control breathing

Email: Tudor Toma - t.toma@ic.ac.uk
News from The Scientist 2001, 2(1):20010913-03

Published

13 September 2001

Increased ventilation in response to hypoxia is essential for survival and has been investigated for over a century, but the fundamental biochemistry behind this response remains unclear. In September 13 Nature, Andrew Lipton and colleagues from University of Louisville, Louisville, Kentucky, show that S-nitrosothiols (SNOs — molecules related to nitric oxide) signal the brain ventilatory response to hypoxia and are of central importance to the regulation of breathing.

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