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Chromatin at centromeres
A novel separation technique shows that chromatin fibres from the centromere are more compact.
Email: Jonathan B Weitzman - jonathanweitzman@hotmail.com News from The Scientist 2001, 2(1):20011012-01
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Chromatin fibers adopt higher-order structures that define chromosomal regions with distinct functional properties. In the October 9 Proceedings of the National Academy of Sciences, Nick Gilbert and James Allan, from the University of Edinburgh in Scotland, UK, describe the use of analytical sucrose gradient sedimentation to examine chromatin fibres released from centromeric heterochromatin (Proc Natl Acad Sci USA 2001, 98:11949-11954).
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