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by Jonathan B Weitzman

RESEARCH ROUND-UP

Sequencing Salmonella
The sequencing of two Salmonella genomes provides insights into the virulence of bacterial strains that cause typhoid fever and gastroenteritis.

Email: Jonathan B Weitzman - jonathanweitzman@hotmail.com
News from The Scientist 2001, 2(1):20011025-01

Published 25 October 2001

There are about 16 million cases of typhoid fever throughout the world each year. In the October 25 Nature, Parkhill et al. report the complete genome sequence of the pathogenic culprit, Salmonella enterica serovar Typhi CT18 (Nature 2001, 413:848-852). The drug-resistant strain has a genome of 4.8 Mb containing over two hundred pseudogenes, some of which correspond to virulence genes in Salmonella typhimurium.


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