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Too much oxygen kills stem cells
Email: Tudor Toma - t.toma@ic.ac.uk News from The Scientist 2001, 2(1):20011113-02
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Oxygen is an important environmental factor, which has received rather little attention in culturing stem cells and other progenitor cells. In November Journal of Cellular Physiology, Marie Csete and colleagues from University of Michigan Medical School, Ann Arbor, US, show that too much oxygen can kill stem cells, slow growth and even trigger an alternate developmental pathway that converts pre-muscle stem cells into fat cells.
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