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by Tudor Toma

RESEARCH ROUND-UP

The missing link

A gene on chromosome 5q may explain the link between microorganism infection and reduced asthma susceptibility.

Email: Tudor Toma - t.toma@ic.ac.uk
News from The Scientist 2001, 2(1):20011203-02

Published

3 December 2001

The increasing prevalence of asthma in industrialized societies may be a consequence of improved hygiene levels and a reduction in the incidence in infections such as tuberculosis and hepatitis A. But, the molecular mechanisms that would help to explain these theories remain elusive. In November 28 Nature Immunology Jennifer McIntire and colleagues from Stanford University, Stanford, US show that Tim1 gene on chromosome 5q may explain the inverse relationship between hepatitis A virus (HAV) infection and reduced asthma susceptibility.


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