The Scientist : New lipid-lowering drugs [3/12/2001]

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by Tudor Toma

RESEARCH ROUND-UP

New lipid-lowering drugs

Compounds that directly bind to a sterol regulating protein can lower low-density lipoprotein cholesterol levels.

Email: Tudor Toma - t.toma@ic.ac.uk
News from The Scientist 2001, 2(1):20011203-03

Published

3 December 2001

Drugs such as statins can reduce high plasma levels of the low-density lipoprotein (LDL) cholesterol that is a significant risk factor for atherosclerosis. In December Nature Medicine Thierry Grand-Perret and colleagues from GlaxoSmithKline, France showed that compounds that bind directly to the sterol regulating protein SCAP, could lower cholesterol levels via a mechanism other than that employed by the statins.

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