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Key to 'wasting syndrome'
Email: Tudor Toma - t.toma@ic.ac.uk News from The Scientist 2001, 2(1):20011210-02
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A reduction in albumin production can cause of cachexia in patients with cancer or chronic inflammatory conditions, but the mechanism behind this inhibition remains unknown. In December 3 European Molecular Biology Organization Journal, Martina Buck and colleagues from VA San Diego Healthcare System and University of California, San Diego, show that tumor necrosis factor alpha (TNF-α) is the key molecule in the prevention of albumin production in chronic diseases.
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