The Scientist : Regulating adeno-associated virus [11/12/2001]

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by Jonathan B Weitzman

RESEARCH ROUND-UP

Regulating adeno-associated virus

A genetic screen has identified a cellular protein that can regulate the replication and production of the potential gene therapy-vector, adeno-associated virus.

Email: Jonathan B Weitzman - jonathanweitzman@hotmail.com
News from The Scientist 2001, 2(1):20011211-01

Published

11 December 2001

Adeno-associated virus is an attractive vector for gene therapy as it is non-pathogenic and integrates into a specific site in the human genome. In the December 11 Early Edition of the Proceedings of the National Academy of Sciences, Toni Cathomen and colleagues, at The Salk Institute for Biological Studies in California describe a genetic screen for cellular proteins that can bind to a viral DNA sequence important for replication and integration (Proc Natl Acad Sci USA, 2001 10.1073/pnas.261567198).

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