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Double mutations
A high-throughput strategy identifies synthetic lethality of thousands of yeast genes.
Email: Jonathan B Weitzman - jonathanweitzman@hotmail.com News from The Scientist 2001, 2(1):20011214-01
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The vast majority of genes in the yeast genome are non-essential suggesting significant functional redundancy. In the December 14 Science, Amy Tong and colleagues describe an approach for high-throughput synthetic-lethal analysis in yeast (Science 2001, 294:2364-2368).
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