The Scientist : A mechanism of COX-2 excess in tumors [18/12/2001]

Supplements

Survey Series

The Scientist Daily

Science headlines delivered daily.
Register today.

For Advertisers

by Tudor Toma

RESEARCH ROUND-UP

A mechanism of COX-2 excess in tumors

Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells.

Email: Tudor Toma - t.toma@ic.ac.uk
News from The Scientist 2001, 2(1):20011218-02

Published

18 December 2001

Cyclooxygenase-2 (COX-2) is a rate-limiting enzyme in prostaglandin biosynthesis with a potential role in promoting colon carcinogenesis, but the mechanism of COX-2 overexpression remains unknown. In December 1 Journal of Clinical Investigation, Dan Dixon and colleagues from University of Utah, Salt Lake City, USA, show that altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells.

Password

> Forgot Password?
> FAQ
> Subscribe

Subscribing to The Scientist is easy and inexpensive.

And you can choose from many options. Try us out with an online day pass starting at only $4.95. Or, get it all with unlimited online access to The Scientist Archive and door-to-door delivery of our monthly print magazine.


	The Scientist also offers site licenses to institutions and organizations. When your librarian adds The Scientist to the library's collection, you can get unlimited online access through your place of work or study. Recommend The Scientist today