The Scientist : Interferon gamma's other face [21/12/2001]

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by Tudor Toma

RESEARCH ROUND-UP

Interferon gamma's other face

Email: Tudor Toma - t.toma@ic.ac.uk
News from The Scientist 2001, 2(1):20011221-02

Published

21 December 2001

Autoimmune disease such as myocarditis involves an excess of interleukin-12 (IL-12) generating subsequent production of interferon-gamma (IFN-γ). Non-specific immunosuppressive drugs are prescribed for the treatment of these conditions. But, in December 18 Circulation, Marina Afanasyeva and colleagues from Johns Hopkins University School of Medicine show that suppressing IFN-γ or the entire immune system is unlikely to be the best way to treat autoimmune disease.

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